Connective tissue diseases

Autoimmune connective tissue diseases are a heterogeneous group characterized by the abnormal structure or function of one or more of the elements of connective tissue, i.e. collagen, elastin or the mucopolysaccharides.

Classically, the following diseases belong to this group:

  • SLE (systemic lupus erythematosus)
  • Scleroderma
  • Dermatomyositis/polymyositis
  • Sjögren's syndrome
  • Mixed connective tissue disease

The detection of specific autoantibodies, the so-called antinuclear antibodies (ANA), may support the diagnosis of autoimmune connective tissue diseases, and help in differential diagnosis as well as in prognosis.



Immunodiagnostics offers a variety of tests to support the diagnosis of connective tissue diseases.